An anti-fouling aptasensor for detection of thrombin by dual polarization interferometry.
نویسندگان
چکیده
An anti-fouling surface was designed to effectively resist nonspecific protein adsorption using dual polarization interferometry, based on which the aptasensor for detection of thrombin was fabricated according to the specific interaction between thrombin and its 15-mer aptamer.
منابع مشابه
Optimisation and Characterisation of Anti-Fouling Ternary SAM Layers for Impedance-Based Aptasensors
An aptasensor with enhanced anti-fouling properties has been developed. As a case study, the aptasensor was designed with specificity for human thrombin. The sensing platform was developed on screen printed electrodes and is composed of a self-assembled monolayer made from a ternary mixture of 15-base thiolated DNA aptamers specific for human thrombin co-immobilised with 1,6-hexanedithiol (HDT)...
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عنوان ژورنال:
- Chemical communications
دوره 51 26 شماره
صفحات -
تاریخ انتشار 2015